Endocrine Abstracts

Introduction: High circulating levels of some but not all unsaturated fatty acids (UFAs) can be related with reduced insulin sensitivity and glucose uptake in skeletal muscle. The real mechanisms by which UFAs impair the insulin sensitivity need to be clarified; nevertheless the UFA’s effects in the regulation of activity and/or expression of some transcriptional factors such as, nuclear factor κB (NFκB), hypoxia inducible factor-1a (HIF-1a), peroxisome prolifer...