ECE2011 Poster Presentations Neuroendocrinology (36 abstracts)
Hormonal disorders in patients with acromegaly in Khorezm region, Republic of Uzbekistan
Rikhsieva Urmanova 1, , Sh O Khodjaev 1, , Sh A Eshmetov 1, , M A Rakhmetova 1, , F S Khodjaeva 1, & B A Azizov 1,
1Republican Specialized Scientific-Practical Medical Center of Endocrinology under the Ministry of Health of the Republic of Uzbekistan, Tashkent, Uzbekistan; 2Tashkent Medical Pediatric Institute, Tashkent, Uzbekistan.
Aim: To study spectrum of hormonal disorders in patients with acromegaly, residents of Khorezm region, Republic of Uzbekistan.
Materials and methods: We examined 22 acromegalics (9 men and 13 women, mean age 39.8 years), residents of Khorezm region, Republic of Uzbekistan. All patients were clinically and biochemically examined with their hormonal parameters, such as levels of GH, LH, FSH, IGF1, prolactin, cortisol and TSH measured, ECG, perimetry and pituitary CT/MRI performed. In 15 examinees (68.2%) the latter procedure helps reveal pituitary macroadenomas.
Results: Mean levels of hormones were found as follows: GH 48.9 ng/ml, LH 3.5 mIU/l, FSH 2.9 mIU/l, IGF1 756 nmol/l, cortisol 320 nmol/l, prolactin 22.8 ng/ml. Two of the patients underwent surgery; three persons received radiotherapy and 17 are still on drug therapy preferentially with dophamine agonists.
Conclusions: Results of investigations indicate the decompensate in most patients examined.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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