Endocrine Abstracts

Aim: To estimate QOL and intensity of depression symptoms in T1DM patients.

Materials and methods: Total 53 T1DM patients (26m, 27f), mean age (M±σ) 33.6±2.7 years (20.00–54.00) and 35 of the control group (17m, 18f), mean age 34.8±2.9 years (22.00–50.00) were provided with the questionnaire of Medical Outcomes Study 36-Item Short-Form Health-Survey, Beck depression inventory and Test for estimation of subjective control level.

Results: The patients with HbA1c <7% the parameters of Role-Physical, Role-Emotional, Mental Health (P<0.05) were higher than in patients with HbA1c≥7%. The negative correlation of expressiveness of depression symptoms with GH (r=−0.54; P<0.05) were obtained. The expressiveness of depression symptoms is lower in HbA1c<7% T1DM patients to compare with HbA1c≥7% Me 21.8 (11.3; 45.2) vs Me 11.3 (8.1; 11.3), (t=−2.053; P=0.057). By the scale of ‘Total internality’ the average level was 73%, the high level – 27%, the low level – 0%; by the scale of ‘Internality of achievements’ the average level consisted 36.5%, the high level – 63.5%, the low level – 0%; ‘Internality of failures’ the average level – 54.5%, the high level – 45.5%, the low level – 0%; ‘Internality of family relations’ the average level was 54.5%, the high level – 27.3%, the low level – 18.2%; ‘Internality of industrial relations’ the average level was 82%, the high level – 18%, the low level – 0%; ‘Internality of interpersonal attitudes’ the average level – 27.2%, the high level –27.2%, the low level – 43.8%; ‘Internality of health and disease’ the average level was 64%, the high level – 36%, the low level – 0%.

Conclusion: The evident depression in 38% of patients testifies to the unfavorable emotional state at T1DM. Higher physical, emotional, psychological health and less expressiveness of depression symptoms in compensation patients underline the urgency of achievement of aim levels of T1DM compensation.