Endocrine Abstracts

Aim: To evaluate the paediatric specialist diabetes nurse (PDSN) delivered 24 h emergency telephone contact service for families with children and young people with type 1 diabetes within Hull and East Yorkshire Hospitals NHS Trust.Methods: A prospective audit of telephone calls received by the 2 PDSNs over a 15-month period between 1 July 2005 and 30 September 2006 for out of hours advice. All the phone calls were logged into a database and details of t...

Introduction: Optimising management of diabetes in school is critical especially with more children being commenced on intensive insulin regimens. Partnership between families, school and caregivers is essential to enhance safety and satisfaction with the educational experience for students.Methodology: We gathered information on facilities in schools for children with T1D from our district hospital by telephonic questionnaire. The questions related to p...

Background: Obese young people are likely to suffer significant morbidity in adult life. Successful intervention during adolescence may have far-reaching benefits. Evidence is emerging that patient-responsive clinical services may deliver improved outcomes.Aims: To assess the perceptions of obese young people about weight and weight-management services.Method: Annonymised, postal questionnaire survey of 116 obese young people (9&#1...

Background: The pancreatic β-cell KATP channel plays a key role in glucose stimulated insulin secretion and is encoded by the genes ABCC8 and KCNJ11. Recessive mutations in ABCC8/KCNJ11 cause severe medically unresponsive HH. Recently, dominant mutations in these genes have been described that cause mild, medically responsive HH. Controversy exists on whether these dominant ABCC8/KCNJ11 mutations predispose to diabetes mellitus in ad...

Background: ISPAD clinical practice consensus guidelines 2006–7 defined DKA as: blood glucose >11 mmol/l in presence of venous pH <7.3 or bicarbonate <15 mmol/l, ketonaemia and ketonuria. The level of ketonaemia or ketonuria was not specified. Blood ketones can be checked easily using a blood ketone meter (Optium). In our institution we have been measuring them on all children admitted with suspected DKA over the last 5 years. A blood ketone level of >3.0 ...

Introduction: Tight metabolic control reduces the risk of microvascular complications in individuals with type 1 diabetes (T1DM). Multiple studies have shown improvements in quality of life (QOL) in children following the introduction of continuous subcutaneous insulin infusion (CSII) but metabolic outcomes have been more variable. This audit looked at metabolic parameters at long-term follow up in children and adolescents using CSII over 3 years.Methods...