Endocrine Abstracts

We report a case of 28-year-old girl with panhypopituitarism and ectopic neurohypophysitis due to absent pituitary stalk. She was admitted to endocrinology policlinic with short stature, growth retardation and primary amenorrhea. Basal hormones indicated tahat she has secondary hypothyroidism, adrenal insufficiency, hypogonadism and GH insufficiency. Peak cortisol response to the short ACTH test was normal but inadequate to insulin tolerance test. The other dynamic pituitary function tests showed totally anterior pituitary hormone deficiency. Magnetic resonance imaging of brain revealed an ectopic posterior pituitary tissue and absent pituitary stalk. We started to hormone replacement therapy. Because this disorder is usually shown in the pediatric age group, we report an adult patient with ectopic posterior pituitary tissue and absent pituitary stalk and totally anterior pituitary hormone deficiency.

Keywords: Ectopic posterior pituitary, hypopituitarism, absent pituitary stalk.