ea0022s28.2 | Hypothalamic networks and energy homeostasis | ECE2010
Lopez Miguel
The ‘classical’ hypothalamic neuropeptide view of feeding regulation has been extensively reviewed and revised during the last few years. Accumulating evidence indicate that pharmacological and genetic modulation of lipogenesis de novo in the hypothalamus, through selective pharmacologic and genetic manipulation of acetyl-CoA carboxylase (ACC), AMP-activated protein kinase (AMPK), carnitine palmitoyltransferase-1 (CPT1), fatty acid synthase (FAS) and malonyl-C...