Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2010) 22 P88

Clincal Centre of Vojvodina, Clinic of Endocrinology, Diabetes and Metabolic Disorders, Novi Sad, Serbia.


Many studies show insufficient and inadequate vitamin D and calcium levels in postmenopausal women with osteoporosis, thus emphasising the need for supplementation therapy.

Aim of the study: To determine vitamin D (25(OH)D) and ionised calcium levels in women treated for postmenopausal osteoporosis at our Clinic in the course of year 2009.

Materials and methods: We prospectively followed up 116 women at the age of 59.38±5.55 (minimal age 48, maximum age 69). The diagnosis of osteoporosis was established by dual X-ray absorptiometry (DXA) of spine and hip. Levels of 25(OH)D and ionised calcium were determined by standard laboratory measurements.

Results: Mean spine T score value was −3.07±0.47 (minimal – 4.5, maximal – 2.6). Average 25(OH)D level was 45.12±16.68 nmol/l (minimal 10 nmol/l, maximal 81 nmol/l). Fifteen women (12.93%) had levels of <25 nmol/l (group I). In the group II there were 57 women (49.14%) with the levels between 25 and 50 nmol/l (group II). Group III consisted of 39 women (33.62%) with 25(OH)D levels between 51 and 75 nmol/l. Only five women (4.31%) had 25(OH)D levels over 75 nmol/l and they comprised group IV. Average ionised calcium level was 0.97±0.07 nmol/l (minimal 0.90 mmol/l, maximal 1.2 mmol/l). In our groups I, II, III and IV ionised calcium levels were 0.97±0.05, 0.98±0.07, 0.97±0.05 and 1.06±0.08 mmol/l respectively.

Conclusion: Our results show inadequate vitamin D and calcium levels in about 50% women with postmenopausal osteoporosis. Measurements of vitamin D and calcium together with their supplementation in necessary in prevention and treatment of postmenopausal osteoporosis.

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