Endocrine Abstracts

Background and aims: It is well known that most of the pregnancy complications (maternal, fetal, & neonatal) increased noticeably in diabetic pregnancy compared with non diabetics, our aims of this study is the impact of the type of diabetes in pregnancy upon pregnancy outcome.

Methods: This is a crosse study analyzed 210 pregnant women who are undergoing antenatal follow up in diabetic pregnancy clinic, and then delivered in Aljalaa Maternity Hospital, Tripoli – Libya in the period from 1.1.2003 up to 31.12.2004. The diabetic women were categorized by the type of diabetes into 3 categories based on the WHO criteria (IDDM, NIDDM,GDM).

Results: GDM represent about half cases of diabetes associated with pregnancy (49%), then NIDDM which represents about 33% & IDDM represent about 18%. pregnancy- induced Hypertension (PIH), pre –Eclampsia (PE),% of cesarean section, polyhydramnios, preterm labour (PL) prelabour rapture of membrane (PLROM), Macrosomia, congenital malformation(CM), prenatal mortality (PNM), R D S, Neonatal metabolic abnormalities, are presented in the table.

Conclusions: GDM increases chance of C/S, induction, Polyhydramnios & PLROM, while IDDM increases rate of PIH & PE, while, incidence of prematurely, IUFD & IUGR increases with IDDM, however Macrosomia increases NIDDM. For neonatal complication IDDM associated with highest risk of CHD which comments CM, hypocalcaemia & PNM, while NIDDM increases chance of polycythemia & RDS and GDM increases rate of hypoglycemia and hyperbilirubinemia. This study revealed that despite the improvement of medical care still the diabetic pregnancy associated with highly unaccepted percentage of adverse outcome compared with non diabetic.