Endocrine Abstracts

Pathophysiological mechanisms of endocrine diseases (and diabetes mellitus type 2 (DM2) among them) impacts person’s health perception and health related behavior as measured by the health related quality of life.

Aim: To compare peculiarities of health related quality of life in patients with DM2 and other endocrine diseases under hospital treatment.

Methods: Of 60 patients with DM2 and 71 patients with other endocrine diseases from the Department of Endocrinology of University Hospital were investigated by using WHOQoL-100 questionnaire.

Results: Physical domain of quality of life in patients with DM2 (11.4±2.4 vs 12.5±2.8, P=0.022), individuality domain (11.5±2.5 vs 13.2±2.6, P<0.001) and spirituality domain (11.3±3.3 vs 12.7±3.3, P=0.022) were significantly lower than in patients with other endocrine diseases, showing worse quality of life. Global score of health related quality of life showed tendency to be lower in DM2 patients than in patients with other endocrine diseases (11.6±2.7 vs 12.3±2.6, P=0.097).

In patients with DM2 significant correlations between BMI and individuality domain (r=−0.307, P=0.020) and between duration of illness and individuality domain (r=−0.264, P=0.047) were detected.

In conclusion: The impact of diabetes mellitus type 2 on psychological well – being as measured by health related quality of life questionnaire is more expressed than this of other endocrine diseases. The pattern of impairment may be helpful in planning psychological rehabilitation in DM2.