Endocrine Abstracts

Obesity is the modern medical problem. According to the WHO expert panel the prevalence of obese population worldwide is 300 million and overweight is 750 million.

In the first trimester of 2007, we studied the obese patients in the Iv. Javakhishvili State Medical University’s Department of Endocrinology. The objective of our research was to study the course of subclinical hypothyroidism adjunct with severe obesity, its diagnostic criteria and treatment. Ninety-four patients were studied, with age range 14–53 years. The duration of subclinical hypothyroidism was from 6 to 18 months. There were 72 women and 22 men, who underwent following clinical, laboratory and topical diagnostic investigations: glucose tolerance test, biochemical analyses of blood, electrolytes, coagulation test, urine test, thyroid and abdomen ultrasound assessment, ECG, Laboratory evaluation of following hormones: TSH, FT3, FT4, leptin.

Fifty-five of 95 patients were diagnosed to have BMI more than 40; 4 patients BMI exceeded 30; 27 patients were diagnosed to have subclinical hypothyroidism.

The treatment of the patients included individual low calorie diet, physical activity in combination with potassium iodide and levothyroxine in some cases. The doses of levothyroxine were decreased along with the loss of weight and normalization of TSH. Received results were positive.