Endocrine Abstracts

Aim: To assess the impact of age, sex, duration of diabetes and body mass index confounders on diabetes control in a Jordanian cohort of T2DM at endocrine clinic at KHMC.

Patients and methods: Patients randomly selected over 18 months from outpatient clinic at KHMC in Amman-Jordan. Diabetes control assessed by mean of latest 3 HbA1c and FBS. Patients were divided in 2 groups according to age (<55 years vs >55 years), gender, duration (<10 years vs >10 years) and BMI (normal, overweight, and obese according to WHO criteria). Statistical analysis is performed using SPSS11.5.Good diabetes control is assessed according to ADA criteria.

Results: A total of 405 patients were selected (223 males, 182 females). 115 patients (28.4%) were having a good control with HbA1c <7%. About 25.6% of males and 31.9% of females were having good control (P=0.161).

There was no difference in diabetes control of those <55 years (n=183) versus those >55 years (n=222) (29 vs 28%; P=0.812). Females in both age groups were having none statistically significant better control than males. Of those of DM duration <10 year (n=242), 34.7% were having good control versus only 19% for those >10 year duration (n=163) (P value=0.001, RR=1.83 (1.27–2.62), OR=2.26 (1.38–3.73)). Females were again having a better diabetic control in both duration groups, P=0.024.

There was no difference in diabetic control in all BMI categories studied. Thirty percent of overweight patients were having good control versus <20% in normal and obese patients.

The mean HBA1c in males was 8.1±1.7 vs 7.9±1.5% in females. For the group <10 year, HBA1c was 7.75±1.5 vs 8.32±1.54% in those >10 year. The mean HBA1C of the group aged<55 years was 8.1±1.8 vs 7.9±1.5 in those >55 years of age.

Conclusion: In the Jordanian cohort with T2DM, the diabetic control was modest at 28.4%. Females were having a better diabetic control at all categories. There is no difference in diabetic control when genders, BMI or age confounders were studied.