ea0020s2.1 | β cell proliferation, survival and secretion | ECE2009
Jones Peter
The mechanisms through which pancreatic beta cells recognise and respond to external signals Type 2 diabetes is becoming increasing well understood, but we have less understanding of how the responses of individual cells are integrated within the islet of Langerhans. Islets are heterogenous organs containing a variety of endocrine cell types including beta, alpha, delta and PP cells which synthesise and secrete insulin, glucagon, somatostatin and pancreatic polypeptide, respec...