Endocrine Abstracts

Primary hyperparathyroidism (PHPT) is not an uncommon endocrine disease in regions where there are liberal indications for serum calcium measurements. There is a general consensus that virtually all patients with symptomatic PHPT should undergo an operation. The proportion of patients with mild or ‘asymptomatic’ PHPT varies between 40 and 80% in published reports, but a frequent estimate is that about 50% of all PHPT patients belong to this category.<p class="abs...

The clinical presentation of primary hyperparathyroidism has changed dramatically after increased accessibility to biochemical auto-analysers and the diagnosis is today often made by change in patients without specific symptoms. Operative treatment is recommended in patient with markedly increased calcium levels or typical symptoms. However, the vast majority of patients in the modern clinic do not present organ related symptoms and their calcium levels are only slightly incre...