ea0020eje1 | The <emphasis role="italic">European Journal of Endocrinology</emphasis> Prize Lecture | ECE2009
Arlt Wiebke
This lecture will cover clinical-experimental and molecular studies elucidating the role and regulation of the adrenal steroid dehydroepiandrosterone (DHEA), a crucial precursor of human sex steroid synthesis. DHEA and its sulphate ester DHEAS are the most abundant steroids in the human circulation and their intraadrenal synthesis represents a recent evolutionary development, only observed in higher mammals. Only humans and higher non-human primates show an age-specific patter...