Endocrine Abstracts

Introduction: Satisfactory glycaemic control in children and teenagers with Type 1 diabetes is difficult to achieve. In Wales before 2002 the level of glycaemic control across the Principality in this age group was unknown.Aims: To determine the level of glycaemic control in diabetic children across Wales.To determine if glycaemic control improved from 2002 to 2007.To identify factors that might be responsibl...

Background: Since the DCCT demonstrated that improved glycaemic control reduced complications the goal of diabetes management has been to maintain HbA1c as close to normal as possible. Recent changes by the laboratory to our HbA1c assay, combined with the debate about deanonymised publication of clinic’s HbA1c results, creating the potential for ‘league tables’, focussed our attention on the variation between HbA1c assays.Clinical data: Ou...

Background: Hypercholesterolaemia has been identified as a major risk factor for cardiovascular disease in adults with Diabetes Mellitus (DM), and studies have shown evidence of raised lipid levels in children with Diabetes. However, current NICE guidelines state that ‘Routine screening for elevated blood lipid levels is not recommended for children and young people with type 1 diabetes’; although ISPAD and APEG recommendations are for lipid screening in those over 1...

Introduction: At the start of insulin pump therapy usually only a single basal rate, one insulin correction factor and one carbohydrate ratio are prescribed. Not only does this approach fail to match normal physiology but experience gained over 5 years of providing an insulin pump service found that these settings invariably needed early and frequent adjustment. As a result algorithms were developed to give a more precise pattern of basal rates and correction factors.<p cl...