ECE2008 Poster Presentations Diabetes and cardiovascular diseases (90 abstracts)
Virgen Macarena Hospital, Seville, Spain.
Objective: To study the improvement of metabolic control and patients satisfaction with glucose continuous monitoring systems (Guardian real time).
Material and method: Fifteen DM1 patients studied (age: 33.8±13.40, years of evolution: 17.06±11.32) in intensive treatment (5 multidoses, 10 insulin pump) which were made one 4 days long blind monitoring Period 1 (blind period) with sensor CGMS Gold. Next another monitoring was made with a real time system with alarms of hyperglycemia and hypoglycemia, Guardian RT, Period 2 (real time period). These 2 monitorings were consecutive in each patient, establishing in the second period the levels of alarm of hypoglycemia in 50 mg/dl and hyperglycemia in 200 mg/dl. We studied in both periods: average glycemia, glycemia variability, percentage of time in hyperglycemia (>180), normal glycemia and hypoglycemia (<70). A satisfaction questionnaire about the systems of continuous monitoring was made.
Results:
Period 1 (blind) | Period 2 (R.T) | P | |
Average glyc | 157.17±34.30 (110224) | 137.49±21.99 (115203) | 0.053 |
Variability | 73.72±19.60 (38103) | 48.23±13.20 (2575) | <0.005 |
% High | 32.56±19.25 (7.075.0) | 19.90±13.87 (1.2356.03) | <0.05 |
% Euglycemia | 55.49±17.79 (25.086.0) | 74.98±14.22 (43.9798.77) | <0.005 |
% Low | 11.94±8.04 (0.0029.00) | 5.10±5.16 (017.00) | <0.005 |
Guardian | P | CGSM | |
Satisfaction | 4.2 | NS | 3.8 |
Recommendable system | 5.1 | <0.,05 | 4.1 |
Uncomfortability | 3.8 | NS | 3.1 |
Anxiety | 1.8 | NS | 1.9 |
Interferences with | |||
Job | 1.3 | <0.05 | 2.5 |
Social life | 1.1 | <0.05 | 2.1 |
Physical activity | 2.7 | NS | 3.1 |
Sexual life | 2.5 | <0.05 | 3.5 |
Sleep quality | 1.5 | NS | 2.3 |
Conclusions: We observed during the monitoring in real time:
Longer time in normal glycemia with less frequency of hypoglycemia and hyperglycemia.
Smaller glycemia variability.
The monitoring in real time could be useful tool at the time of assuring a better metabolic control and to diminish the exhibition to hypoglycemias.
GURADIAN RT did not generate greater anxiety than the GCMS interfering to a lesser extent in the daily life of our patients.