ECE2008 Poster Presentations Diabetes and cardiovascular diseases (90 abstracts)
Metabolic control and quality of life in patients with DM1 and insulin pump therapy
Isabel Serrano , Cristobal Morales , Silvia Maraver , Guillermo Martinez de Pinillos , Juan Manuel Garcia-Quiros , Monica Tome , Carmen Cuesta & Angel Sendon
Virgen Macarena Hospital, Seville, Spain.
Objectives: To value the quality of life improvement and metabolic control in patients with DM1 in the 2 first years of treatment with insulin pump therapy.
Material and methods: We studied 33 DM1 patients, 16 men (48.5%) and 17 women (51.5%), with average age of 34.2±12.2 and 16.3±10.21 years of disease. Pump indication was hypoglycemia in 10 (30.3%), badly metabolic control in 14 (42.4%), pregnancy in 5 (15.2%) and glycemic inestability in 4 (12.1%). Following parameters pre-treatment were valued to the 3, 12 and 18 months: HbA1c, total insulin (IU/kg), BMI, glycemia average, hypoglycemias and number of controls/day. All filled the WHO questionnaire of treatment satisfaction previous to implantation of I.S.C.I., to 6 and 12 months.
Results:
| Pre | Beginning | 6 m | 12 m | 18 m | |
| HbA1c | 8.0±1.9 | 7.5±1.6† | 6.8±1.3† | 6.4±0.5* | 6.3±0.7 |
| IU/kg | 0.76±0.3 | 0.56±0.3† | 0.57±0.2† | 0.65±0.3 | 0.45±0.1 |
| BMI | 25.4±4.3 | 25.05±4.0 | 25.37±3.9 | 25.14±3.2 | 25.89±2.6 |
| Glycemia | 157.2±32 | 155.4±24.5 | 151.7±50.1 | 156.5±52.1 | 151.4±12.3 |
| Variability | 86.7±20.3 | 83.2±20.7 | 73.3±23.8* | 96.5±45.2 | 79.1±15.1 |
| Hypoglycemias/month | 8.1±6.5 | 10.6±8.2 | 4.5±3.9* | 6.08±5.2* | 4.20±2.4 |
| Controls/day | 1.76±0.8 | 3.59±1.9 | 4.14±1.6 | 3.2±1.2 | 3.46±0.5 |
| *P<0.05; †P<0.01. | |||||
Conclusions: A significant reduction of HbA1c was obtained in patients with insulin pump, specially during the first month. The HbA1c descended before treatment in relation to the educative program. The number of hypoglycemias decreased three months after the beginning. A greater satisfaction with I.S.C.I was observed at the 6 and 12 months.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more