Thyroid dysplasia – 30 cases of lingual thyroids

Eusebie Zbranca; Cristina Preda; Voichita Mogos; Letitia Leustean; Carmen Vulpoi; Bogdan Galusca; Valeriu Rusu; Radu Negru

P477

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Endocrine Abstracts (2007) 14 P477

ECE2007 Poster Presentations (1) (659 abstracts)

Thyroid dysplasia – 30 cases of lingual thyroids

Eusebie Zbranca , Cristina Preda , Voichita Mogos , Letitia Leustean , Carmen Vulpoi , Bogdan Galusca , Valeriu Rusu & Radu Negru

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University of Medecine, Iasi, Romania.

Thyroid dysplasia (ectopy, hypoplasia or aplasia) is a common cause of congenital hypothyroidism. Lingual thyroid is a rare embryological aberration caused by failure of migration of the thyroid gland to its normal position in the neck.This retrospective study involved 30 patients with lingual thyroid diagnosed in our Department between 1970–2005. The diagnosis was based on physical examination, evaluation of the mental development (IQ) and following tests:TSH, fT4, ultrasound imaging of the neck and sublingual region and neck scintigraphy. Among the patients with congenital hypothyroidism the incidence of lingual thyroid was 29%. Females (83%)were affected more than males (17%). In our group the age at diagnosis was between 6 months and 35 years. The mental retardation (mild to moderate) was present in 85% of cases. The analysis of physical development reveal growth disturbances in 56% of cases. On the basis of this findings it may be stated that the early diagnosis and treatment are the most important for the normal development of children with lingual thyroid.