ECE2007 Poster Presentations (1) (659 abstracts)
1Dicle University School of Medicine Department of Radiology, Diyarbakir, Turkey; 2Dicle University School of Medicine Department of Endocrinology, Diyarbakir, Turkey.
Background and aim: Carotid intima-media thickness (IMT), as assessed by B-mode ultrasound, is a commonly used clinical marker that reflects systemic burden of atherosclerosis and value of IMT at or above 1 mm at any age is associated with a significantly increased risk of myocardial infarction. On the basis of such findings, we aimed to clarify the relationship between carotid intima-media thickness and anthropometric and metabolic parameters in virtually healthy subjects.
Subjects and methods: A total of 117 apparently healthy subjects were included to the study (age 2068 year, mean age: 43±12, BMI:30.1±7.99 kg/m2). Carotid Intima-media thickness (IMT) was measured with ultrasonography. Subjects were divided into two groups according to their IMT higher than 1 mm (group-1) or not (group-2). Total cholesterol, LDL-cholesterol, triglycerides, Hs-CRP, interleukin-1β, interleukin2, interleukin 6, interleukin 8, Tumour necrosis factor α, BMI, body fat mass with bioelectric impedance and body fat distribution (waist and hip circumference) of two groups were compared with independent t test.
Results: BMI, body fat mass, hip circumference, plasma LDL cholesterol, Hs-CRP levels of group-1 were higher than group-2 (
Conclusions: 1-Carotid intima media thickness are closely related increased BMI, fatmass, hip circumference and LDL-cholesterol levels.
2-Hs-CRP is a useful marker of atherosclerosis.
Group-1 (n=17) | Group-2 (n=100) | P value | |
BMI | 37.6±7.1 | 28.7±7.3 | P=0.0001 |
Body Fatmass | 40.7±15.2 | 24.9±14.3 | P=0.001 |
Hip circumference | 122±18 | 107±14 | P=0.0001 |
Hs-CRP | 7.23±2.95 | 3.67±1.50 | P=0.008 |
LDL-cholesterol | 135.4±29.8 | 108.8±33.2 | P=0.008 |