ECE2007 Poster Presentations (1) (659 abstracts)
Screening and treatment of gestational diabetes and impaired glucose tolerance in Georgia
Natalia Asatiani 1 , Ramaz Kurashvili 2 , Mzia Dundua 3 , Elena Shelestova 1 , Liana Tsutskiridze 1 , Moche Hod 1 , Sergey Smirnov 1 & Victor Vlasov 1
1Georgian Diabetes Center, Tbilisi, Georgia; 2Dep.of Obstetrics and Gynecology, Rabin Medical Center, Tel-Aviv, Israel; 3Novo Nordisk A/S, Copenhagen, Denmark.
Background and Aim: One of the greatest problem in pregnancy, complicated by diabetes is screening and appropriate care for women, whose diabetes is manifested during pregnancy. The study is aimed at gathering epidemiological data on gestational diabetes mellitus (GDM) and evaluating the of appropriate therapy in this condition.
Materials and Methods: Screening for GDM was carried out in – 692 pregnant women. GDM was observed in 3.3% (22 women) and impaired glucose tolerance (IGT) - in 5.05% (35 women). 57 women with GDM and IGT comprised the Group 1 (Gr.). Fifteen pregnant women, who were not screened timely and attended the Center at 10-34 week of gestation with fasting hyperglicemia and ketoacidoses comprised the Gr.2.
Results: In Gr.2 HbA1c (9.5±1.7%) levels at entry were statistically higher, than in Gr.1 (6.3±0.93%)(P=0.000). By the end of the 3rd trimester those indices dropped ((6.3±0.72%; 5.45±0.74% respectively). In Gr.1 following pathologies were observed: pre-eclampsia had 2(3.5%), preterm delivery – 2(3.5%), macrosomia – 9(15.7%), perinatal deaths – 0. In Gr.2: pre-eclampsia had 4(26.6%), preterm delivery – 3(20%), macrosomia – 3(20%), perinatal deaths – 4(26.6%). Mean infants’ birth weight (g) was 586± 323 (Gr.1) and 3 260±445 (Gr2).
Conclusion: Following epidemiological data were obtained for Georgia: IGT (5.05%) and GDM (3.3%). Good glycemia control during pregnancy not always prevents macrosomia, though significantly reduces the risk of pre-eclampsia, preterm delivery and perinatal deaths.
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Endocrine Abstracts
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