Endocrine Abstracts

Diabetes mellitus type 2 (DM2) is affecting physical and psychological health.

Objective: Compare anthropometric data, body composition, lipids levels, emotional state, quality of life (QoL) of DM2 patients and that of healthy persons of the same age.

39 persons (58.1±9.6 years) with DM2 (18 male, 21 female) and 41 healthy persons (54.3±9.9 years) (22 male, 19 female). Profile of Mood State (POMS) used for emotional state evaluation, WHO Brief Quality of Life Questionnair – for QoL.

Results: In male weight (107.6±30.1 vs 86.7±23.1 kg, P=0.008), body mass index (35.0±9.9 vs 28.1±5.4 kg/m², P=0.013), fat mass (37.7±21.0 vs 25.1±12.3 kg, P=0.041), lean mass (69.7±10.6 vs 61.6±11.7 kg, P=0.022), water mass (52.1±9.1 vs 45.1±7.6 kg, P=0.007, waist-to-hip ratio (0.97±0.06 vs 0.91±0.05, P=0.018) were significantly higher in DM2 patients than in controls. In female weight (90.5±14.6 vs 74.5±18.7 kg, P=0.002), body mass index (34.9±6.2 vs 28.0±5.7 kg/m², P=0.013), fat mass (42.0±10.4 vs 30.6±12.2 kg, P=0.003), lean mass (48.5±6.4 vs 43.5±7.8 kg, P=0.05), water mass (38.1±4.8 vs 33.5±4.9 kg, P=0.004), waist-to-hip ratio (0.90±0.4 vs 0.83±0.1, P=0.002) were significantly higher in DM2 patients than in healthy female. In male and female no significant differences between research and control groups in high and low density cholesterol were found. In male, but not female QoL (79.3±8.6 vs 85.3±8.7, P=0.032), POMS vigor (−11.8±3.8 vs −15.8±4.8, P=0.009) were significantly lower in DM2 than in control group. Significant correlations were found in male between vigor and waist-to-hip ratio (r=0.347, P=0.041), in female between vigor and water mass (r=0.313, P=0.049), POMS total and waist-to-hip ratio (r=0.362, P=0.046), depression and low density cholesterol (r=0.430, P=0.028), vigor and lean mass (r=0.385, P=0.014).

In conclusion: Weight, body mass index, fat mass, lean mass, water mass, waist-to-hip ratio were significantly higher in male and female; quality of life and vigor were significantly lower in DM2 male than in healthy persons of the same age.