ECE2007 Poster Presentations (1) (659 abstracts)
Fracture risk in diabetic patients
Anna Gusova 1 , Maria Pavlova 1 , Aleksey Alekseenko 2 , Galina Melnitchenko 1 , Leonid Silin 1 , Natalia Zaytseva 1 & Vyacheslav Pronin 1
1Sechenov Moscow Medical Academy, Moscow, Russia; 2Local trauma clinic N56, Moscow, Russia.
Diabetes mellitus (DM) is accompanied with a variety of metabolic changes in different systems including bone. In several previous studies it was shown that DM type 1 is associated with a decreased mineral density, whereas the data regarding DM type 2 are still controversial.
In the present study we examined the risk of different bone fractures in diabetic patients visiting local trauma clinic during one year (total area population 50.500). The incidence of fractures in general population was 1.9%, whereas in diabetic population it was twice higher (4.4%; χ2=27.4; P<0.001). Fracture of distal forearm was the most prevalent type of fractures in diabetic patients (32.5%), followed by fractures of the phalanges (27%), proximal humerus (15%) and tibial bone (12.5%). Fractures of distal forearm and humeral fractures were less prevalent in a general population (20.2% and 12.8%, correspondingly), compared to diabetic group, although the any statistical significant difference was found only for fracture of distal forearm (χ2=2.8; 0.05<P<0.10). The incidence of fractures in other locations did not differ between two groups.
In conclusion, our data indicate that patients with diabetes have an increased total fracture risk, mainly due to higher incidence of the fractures of distal forearm. There is no difference in risk of fractures of other locations in diabetic patients compared to general population.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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