Endocrine Abstracts

Aim: Serum calcium levels have a relation glucose homeostasis and weight management, and controversies in findings. This study carried out relationship between serum calcium levels and various metabolic parameters in obese Turkish Women.

Materials and methods: Subjects for this study were 3544 overweight or obese Turkish women with mean level of serum calcium 9.4 md/dl. According to mean calcium level, they divided group I having >9.4 mg/dl and group II having ≤9.4 mg/dl. Thereafter, we determined and compared body compositions (body mass index, abdominal fat mass), resting blood pressures, plasma lipids and lipoprotein levels, glucose homeostasis.

Results: A total of 715 (20.2%) patients were identified as overweight (BMI 25–30 kg/m²) and 2831 (79.8%) were identified obese (BMI ≥30 kg/m²). Mean fasting glucose, total cholesterol, triglycerides levels, systolic and diastolic blood pressures were significantly different in high calcium group (n=1710, 48.2%) than low calcium group (n=1834, 51.8%). Fasting glucose, total cholesterol,, HDL-cholesterol, triglycerides, insulin levels, HOMA values, systolic and diastolic blood pressures were positively correlated with calcium levels, not correlated with age, body mass index, waist and hip circumferences.

Conclusion: Our data showed that there was no relation between serum calcium levels and body fat distribution. Altough there was no effect on obesity, different metabolic parameters such as fasting glucose, total cholesterol, triglycerides levels and blood pressures were affected and correlated with serum calcium levels. It should be careful during a slimming program with included high calcium diet in obese or overweight women.