Endocrine Abstracts

Fibroblast growth factor 1 gene (FGF1) is located within the blood pressure quantitative trait locus on human chromosome 5 and encodes a multifunctional regulator of cardiovascular function and structure. To dissect associations between blood pressure and this positional candidate gene 51 FGF1 single nucleotide polymorphisms identified either in sequencing or/and public databases were genotyped in 629 individuals from 207 white hypertensive families. Linkage disequilibrium map...