Endocrine Abstracts

Multiple Endocrine Neoplasia (MEN) type 1 and type 2 are autosomal dominant familial cancer syndromes characterised by the development of multiple endocrine tumours that can present at different sites, at different times. Management can be complex and requires a coordinated, multi-disciplinary approach that covers presentation, diagnosis, treatment and long term review. This may not match up with some established models of service delivery and challenges us to develop clinical...

In the West of Scotland there is a monthly joint Genetic / Endocrine clinic aiming to centralise management and ensure appropriate screening of individuals with, or at risk of, hereditary endocrine disorders including MEN. This clinic has a designated Genetic Counsellor as well as Consultant Geneticist, Endocrine Nurses and Endocrine Clinicians. The successful collaboration between the departments has led to an increase in expertise on both sides and awareness of the other spe...

Multiple endocrine neoplasia type 2 (MEN2) is an autosomal dominant condition that is rare in childhood. MEN2 is sub-classified into three categories that all include familial medullary thyroid carcinoma (MTC). Familial MTC has no other associated tumours. MEN2A is characterised by MTC, phaeochromocytoma and parathyroid tumours and MEN2B consists of MTC, phaeochromocytoma, ganglioneuromatosis and usually a Marfanoid habitus. The identification of RET as the causative gene has ...

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