ECE2006 Poster Presentations Endocrine tumours and neoplasia (116 abstracts)
An intrasellar germinoma with normal cerebrospinal fluid β-HCG concentration misdiagnosed as hypophysitis
Sinan Tanyolac 1 , Ayse Cikim 2 , Nese Ozbey 1 , Altay Sencer 3 , Ramaza Kurt 3 , Serra Sencer 4 , Inan Turantan 3 & Senay Molvalilar 1
1Istanbul University Istanbul Faculty of Medicine Departmant of Internal Medicine Division of Endocrinology and Metabolism, Istanbul, Turkey; 2Inonu University, Faculty of Medicine, Endocrinology and Metabolism, Malatya, Turkey; 3Istanbul University Istanbul Faculty of Medicine Departmant of Neurosurgery, Istanbul, Turkey; 4Istanbul University Istanbul Faculty of Medicine Departmant of Radiodiagnostic, Istanbul, Turkey.
Intracranial germinomas are malignant neoplasms which are supposed to arise from primitive germ cells failed to migrate to the genital crest during embryonic development. Most of them are located in the intra-suprasellar region and may cause anterior and particularly posterior pituitary hormone deficits. Early establishment of the histological diagnosis is important for optimum treatment planning and a successful outcome. Intracranial germinomas are radiosensitive and potentially curable. In this study we report a case of an intrasellar germinomas leading to infundibular thickening with lymphohistiocytic reaction and normal β-HCG concentrations in the cerebrospinal fluid (CSF).
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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