Endocrine Abstracts

The prevalence of cardiovascular diseases (CVD) has increased sharply in the developing countries and because Type 2 diabetic patients are at increased risk for CVD.

Objective: To determine the prevalence of patients with past hystory of a myocardial infarction or cerebral strok in newly diagnosed type 2 diabetic patients in Georgia.

Design: Cross-sectional study.

Patients: Newly diagnosed type 2 diabetic patients (n=648, age (M±S.D.) 53.9±10.11; female 58%).

Measurements: Blood pressure, body mass index, past history of CVD.

Results: There was an linear relationship between BMI and age at diagnosis of type 2 diabetes (P <0.01). Adults with type 2 diabetes were more obese (BMI 30.0±5.34 kg/m²) versus control subjects (BMI 27.6±4.51 kg/m²; P <0.001). Patients, with newly diagnosed type 2 diabetes without an arterial hypertension had the greater prevalence of a past hystory of myocardium infarction (13/299), than persons of control group (0/194, χ²=8.66. P=0.003). According to present data, we can make conclusion, that atherosclerotic vascular complications starts to develop long before the onset of clinical diabetes, due to metabolic disorders during the prediabetic state. In newly diagnosed type 2 diabetes patients, the risk of coronary heart disease (CHD) is more prevalent, than the risk of cerebrovascular atherosclerotic disease. At the stage of newly diagnosed diabetes the risk of cardiovascular disease is more frecuently present in male patients, than in female. The coexistence of hypertension and type 2 diabetes significantly rises the risk of cerebrovascular disease, and not significantly changes the high risk of CHD disease. In newly diagnosed type 2 diabetes patients with hypertension the risk of cerebro-vascular disease is 4 fold prevalent in the case of male patients.