<emphasis role="italic">In vivo</emphasis> imaging of signalling

Optical Projection Tomography (OPT) is a novel, unique and fast whole mount imaging technology which generates stunning 3D images plus virtual sections (in 3 orientations) of small biological specimens (115 mm). It is ideal for analysis of patterns of gene expression and protein distribution as it can be used with both visible (e.g. LacZ) and fluorescent stains. OPT can also be used on unstained tissue. The virtual sections give cellular levels of resolution, whilst the ...

0 shares

ea0011s86 | <emphasis role="italic">In vivo</emphasis> imaging of signalling | ECE2006

A mouse reporting on estrogen receptor (ER) transcriptional activity to understand the complexities of female physiology in mammals

Maggi A

We recently generated a transgenic reporter mouse, ERE-Luc, to study ER transcriptional activity in pathophysiological states. In this model, luciferase synthesis is strictly associated with transcriptional activity of both ERα and ERβ, independent from the activity of receptors related to ERs. This enables to apply non-invasive imaging technologies to visualize ERs transcriptional activity in vivo, allowing to follow ERs activity in time in several organs in ...

0 shares

ea0011s87 | <emphasis role="italic">In vivo</emphasis> imaging of signalling | ECE2006

Micro PET-ing in mice

Abstract unavailable...

0 shares

Endocrine Abstracts

8th European Congress of Endocrinology incorporating the British Endocrine Societies

Symposia

OPT: a novel wholemount imaging technology for visualising gene & protein expression

A mouse reporting on estrogen receptor (ER) transcriptional activity to understand the complexities of female physiology in mammals

Micro PET-ing in mice

BiosciAbstracts