ECE2006 Poster Presentations Thyroid (174 abstracts)
Modifications in the frequency of presentation and the TNM stage at diagnosis of thyroid carcinoma in the last decade in Valencia (Spain)
J Yanini , R Casañ , K García , A Jover , M Gómez , E Solá , C Morillas , H Peña , ML Muñoz & A Hernández
Universitary Hospital Doctor Peset, Valencia, Sweden.
Aims: The aim of the present study was to evaluate the relative frequency of histological categories of thyroid malignant neoplasms. Another aim was to evaluate the TNM stage differentiated thyroid carcinoma (DTC) at the time of initial presentation in Valencia Community (Spain).
Methods: Histopathology and TNM stage thyroid carcinomas diagnosed of thyroid carcinoma diagnosed between 1998 and 2005 in our endocrinology service, were recorded.The sample was divided in: 1978–1994 (107 cases) and 1994–2005 (216 cases).
Results: The frequency of histological subtypes during both periods is shown in the table below:
| 1978-1994 | 1994-2005 | |||
| Absolute frequency | Relative frequency | Absolute frequency | Relative frequency | |
| Papillary* | 80 | 74% | 207 | 81% |
| Follicular | 16 | 15% | 15 | 6% |
| Hurtle | 5 | 5% | 10 | 4% |
| Medullary | 3 | 3% | 8 | 3% |
| Anaplastic | 2 | 2% | 3 | 1% |
| Lymphoma | 1 | 1% | 3 | 1% |
| Others | 0 | 0% | 10 | 4% |
| Total | 107 | 100% | 256 | 100% |
Regarding: DTC, the stage at diagnosis during both period is shown in the table below:
| T1 | T2 | T3 | T4 | |
| 1978-1994 | 77% | 14% | 6% | 3% |
| 1994-2005 | 90% | 7% | 2% | 1% |
| No | N1 | Mo | M1 | |
| 1978-1994 | 81% | 19% | 96% | 4% |
| 1994-2005 | 91% | 9% | 99% | 1% |
Papillary-follicular carcinomas have been included in papillary carcinomas.
Conclusion: We have found an increase in the relative frequency of papillar carcinoma over follicular carcinomas.The relative frequency of the other histological subtypes has not changed. DTC have been diagnosed earlier in the second period probably owing to an increase in cervical image testing performed for extrathyroid pathology. Our data support the growing utility of low-risk DTC protocols.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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