Endocrine Abstracts

Inhibins are members of the Transforming Growth Factor-β (TGF-β) superfamily of pleiotrophic growth and differentiation factors that includes activins and bone morphogenetic proteins (BMPs). Inhibins were characterized originally as providing negative endocrine feedback from the gonads to the pituitary gland to regulate Follicle Stimulating Hormone (FSH) secretion. More recently, inhibin has been shown to antagonise activin and BMP action in engineered cell systems t...