Endocrine Abstracts

Growth hormone (GH) is regulated by two antagonistic hypothalamic hormones, GHRH and somatostatin, plus the liver-derived hormone IGF-I and metabolic signals. Then GH actions are implicated on somatic growth and in the regulation of general metabolism.Developed in the seventies of past century, GH secretagogues (GHS) are small artificial molecules, either peptidyl or non-peptidyl, who actively discharge GH in all animal species so far studied and through...