SFE2002 Poster Presentations Clinical case reports (21 abstracts)
HISTOPLASMOSIS, A RARE CAUSE OF ADDISON`S DISEASE: CASE REPORT
G Vargas 1 , M Monteiro 1 , A Santos 1 , I Calhim 2 , R Pina 2 , M Correia 3 , V Lopes 4 , R Carvalho 1 & H Ramos 1
1Department of Endocrinology, Hospital Geral de Santo Antonio, Porto, Portugal; 2Department of Pathology, Hospital Geral de Santo Antonio, Porto, Portugal; 3Department of Surgery, Hospital Geral de Santo Antonio, Porto, Portugal; 4Department of Microbiology, Hospital Geral de Santo Antonio, Porto, Portugal.
Background: Fungal infections are a rare cause of primary adrenal insufficiency, raising difficulties in the diagnostic and therapeutic approaches.
Case report: A 56 years old diabetic male, who lived in Guinea in 1968, was referred to our inpatients clinic because of a 7,7x3 cm adrenal incidentaloma. He presented with hyperpigmentation, postural symptoms, weakness, fatigue, anorexia and weight loss.
The rapid ACTH stimulation test had a subnormal response and ACTH was
1144 pg/ml. The screening for pheochromocytoma was negative.
He was submitted to left adrenal resection. The other gland had no macroscopic evidence of tumours.
The histological exam identified a fungal agent, Hystoplasma capsulatum.
He is under treatment with Hidrocortisone, Fluodrocortisone and Itraconazole.
Comments: This is a rare cause of Addisons`disease. However, as tuberculosis became less frequent, fungal disease is a more common cause of adrenal gland infection, particularly if the patient lives in an endemic area. The accurate diagnosis has implications in therapeutic approach.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more