ea0004p28 | Comparative | SFE2002
Gonzales-Martinez D
, Howard K
, Bouloux P
, MacColl G
IntroductionKallmann syndrome (isolated hypogonadotrophic hypogonadism and anosmia), is caused by loss of KAL-1 function in the developing human olfactory system. Gene function is also conserved in eukaryotes, including nematodes, chick and rodents. However, the precise role of kal-1 in the developing nervous system is unclear. D.melanogaster an ideal model to study kal-1 function, as many molecular aspects of olfactory development are shared with mammal...