ea0049gp181 | Pituitary | ECE2017
Dal Jakob
, Klose Marianne
, Heck Ansgar
, Andersen Marianne
, Kistorp Caroline
, Nielsen Eigil Husted
, Bollerslev Jens
, Feldt-Rasmussen Ulla
, Jorgensen Jens Otto Lunde
Context: Assessment of disease control in acromegaly depends on GH and IGF-I, but discordant values frequently occur. Further, the role of OGTT-suppressed GH (GHnadir) in somatostatin analogue (SA) treated patients is debated.Objective: To evaluate the effect of targeting either IGF-I or GH during SA treatment.Design: A randomized, investigator-initiated, multicentre trial.Patients and methods: 84 ...