ea0049s15.2 | Metabolic surgery mechanisms to clinical results (Endorsed by the European Journal of Endocrinology) | ECE2017
Mithieux Gilles
Gastric bypass surgery (GBP) promotes early benefits in energy homeostasis in obese diabetic patients, including decreased hunger and improved glucose control. A suggested mechanism associates a decrease in hepatic glucose production (HGP) with an enhanced intestinal gluconeogenesis (IGN), the latter promoting metabolic benefits in energy homeostasis. In addition, bile acids (BA) have emerged as key metabolic regulators, which might account for several anti-diabetic effects. M...