Endocrine Abstracts

35-year lady with BMI of 43 was admitted to local hospital after acute shortness of breath. History of Right calf pain and swelling was evident which raised suspicion of VTE with high likelihood of Pulmonary Embolism. Subsequent CT Pulmonary Angiogram confirmed the same with origin of clot from her leg DVT. She had successfully thrombolysis in intensive care as per hospital protocol. Her high body mass index was thought to be risk factor for blood clots. Her periods were regul...

35-year lady with BMI of 43 was admitted to local hospital after acute shortness of breath. History of Right calf pain and swelling was evident which raised suspicion of VTE with high likelihood of Pulmonary Embolism. Subsequent CT Pulmonary Angiogram confirmed the same with origin of clot from her leg DVT. She had successfully thrombolysis in intensive care as per hospital protocol. Her high body mass index was thought to be risk factor for blood clots. Her periods were regul...

Case: A 34 years old lady presented to the antenatal clinic at 7 weeks gestation with unplanned pregnancy. She had background history of HTN, poorly controlled T2DM and hypercholesterolemia . She continued taking metformin, gliclazide, sitagliptin and simvastatin which were stopped at the booking appointment . Metformin continued and started on insulin. Blood tests at booking showed HbA1c 126, Cholesterol 5.2 , Triglycerides 2.7. She was started on...

Objective: We present this case to emphasize the need to consider the uncommon causes of hypercalcaemia and the importance of history taking.Case report: A 79 year old man with multiple sclerosis was admitted with hypercalcaemia of 3.41 mmol/L, a suppressed PTH and AKI. He was investigated for non-PTH mediated hypercalcemia, having a whole host of investigation. He had normal serum ACE, with no radiological evidence of granulomatou...

Case: A 34 years old lady presented to the antenatal clinic at 7 weeks gestation with unplanned pregnancy. She had background history of HTN, poorly controlled T2DM and hypercholesterolemia . She continued taking metformin, gliclazide, sitagliptin and simvastatin which were stopped at the booking appointment . Metformin continued and started on insulin. Blood tests at booking showed HbA1c 126, Cholesterol 5.2 , Triglycerides 2.7. She was started on...

Objective: We present this case to emphasize the need to consider the uncommon causes of hypercalcaemia and the importance of history taking.Case report: A 79 year old man with multiple sclerosis was admitted with hypercalcaemia of 3.41 mmol/L, a suppressed PTH and AKI. He was investigated for non-PTH mediated hypercalcemia, having a whole host of investigation. He had normal serum ACE, with no radiological evidence of granulomatou...

Introduction: Vitamin D (Vit D) is required for maintaining optimal bone health and there is widespread campaign in the media for its use. There is however lack of awareness among the general public about therapeutic doses which if exceeded can result in harm. We present one such patient who was taking harmful quantities of vit D supplements procured over the internet which resulted in hypercalcaemia and renal failure.Case Description: 50year old lady, N...

Introduction: Bariatric surgery is now a common surgical procedure for weight management recommended by NICE. Complications such as dumping syndrome, micronutrient deficiencies are well documented in the literature. Here we discuss a lesser reported complication of adrenal insufficiency and its management in five patients following gastric bypass surgery.Case reports: All patients presented with one or more of the following symptoms: sweating, anxiety, w...

Introduction: Idiopathic Pituitary atrophy is rare cause of pan hypopituitarism. Various hypotheses were proposed to identify aetiology of idiopathic pituitary atrophy. Still definite cause is not known. There are very few reported cases of pituitary atrophy. We present a case of pituitary atrophy that required complete replacement of pan hypopituirsm to alleviate her symptoms.Case report: About 64 year lady was referred for evaluation of hyponatraemia a...

Introduction: Insulinoma is a neuroendocrine tumour derived from the pancreatic islet cells producing excessive amounts of insulin. It can be seen at every age but mostly seen in females above age 50 years old. Because of nonspecific symptoms 20% of cases are misdiagnosed primarily. Major symptoms and signs are related to hypoglycaemia and become significant due to exercise and fasting. This case reveals the diagnostic difficulty due to hypoglycaemia unawareness.<p class="...