Endocrine Abstracts

Subject: Use of intraoperative ultrasound (iUS) during transshenoidal surgery addresses (a) resection control of macroadenomas and (b) identification of microadenomas, thus avoiding extensive pituitary exploration.Method: (a) For resection control of 33 pituitary macroadenomas and 2 meningeomas a 13 MHz US probe with a perpendicular 10 mm linear field was introduced into the sella after intrasellar resection to investigate the suprasellar and parasellar ...

Introduction: Up to 40% of cases with endocrinologically and surgically proven Cushing’s disease (CD) are MRI-negative1. With intraoperative transsphenoidal ultrasound 72% of microadenomas in CD were identified as hyperechogenic structure2. We report on the first 9 cases with intraoperative use of direct contact high-frequency ultrasound (hf-us) in patients with CD.Patients: All 9 cases (all female, age 31–71 years) reveal...

Introduction: Trans-sphenoidal surgery (TSS) with minimally invasive techniques is the first choice in the treatment of paediatric Cushing’s disease (CD). The question is how can high remission rates be achieved with less invasive investigations and TSS. The developments in our centre treating 100 pediatric Cushing patients with long-term follow-up may add some helpful ideas.Material and methods: Data from our first series 1 (n=55) will be ...

Context: Acromegaly is a rare disease caused by excessive growth hormone (GH) secretion, mostly induced by pituitary adenomas. The care of pregnant women with acromegaly is challenging, in part due to existing clinical data being limited and not entirely consistent with regard to potential risks for mother and child.Objective: To retrospectively examine data on pregnancy and maternal as well as neonatal outcomes in patients with acromegaly.<p class="...