Endocrine Abstracts

Contemporary research data indicate that pancreatic beta cells are sensitive to ionizing radiation. Our recent studies showed a significant (2–3-fold) increase in the type 2 diabetes mellitus (T2DM) incidence in adults exposed to ionizing radiation in a young age within 1986–1990 time period compared to the entire population of Ukraine. Currently there are no data on the time pattern of content of proinflammatory cytokines TNF-α and IL-6 in the clean-up workers ...

Prevalence of diabetes mellitus in the world is constantly increasing and today the type 2 diabetes pandemic is the point of issue. The type 2 diabetes incidence in exposed individuals i.e. the participants of the Chernobyl Nuclear Power Plant accident consequences clean-up works (ChNPP ACUW) in Ukraine in the post-accident years was about 15-21%, which was significantly higher (p<0.0001) than in the non-irradiated persons (3-9%). The adipose tissue is actively in...

Introduction: Accident at the Chernobyl NPP (ChNPP) in Ukraine on the 26th of April, 1986 was followed by the intensive release of a wide range of radioactive elements with affinity to many endocrine tissues. The mentioned radioactive fallout resulted in both internal and external radiation exposure, among others, of the central endocrine structures of the human brain.Methods: We have conducted a retrospective analysis (20–25 years upon radiation ex...

During the Chernobyl nuclear power plant accident (ChNPPA) a mixture of radioactive isotopes, mainly the iodine and cesium, were released, which through inhalation and food, and in some cases along with external exposure had affected the hormone-producing cells of endocrine system. Within days and months after the accident, the thyroid and parathyroids accumulated a significant amount of these isotopes with thyroid gland becoming a secondary emitter, which further increased th...

Several million people in Ukraine and other countries had been exposed to ionizing radiation during the Chernobyl nuclear power plant accident (ChNPPA) on April 26, 1986. The ChNPPA clean-up personnel involved in emergency and recovery works in the 30-kilometer exclusion zone of power plant in the nearest days or months and/or for a long time had received the highest radiation doses due to external gamma-exposure and from incorporated radioactive isotopes with high affinity to...

Parathyroid glands are critical not only for regulation of the phosphorous-calcium metabolism, but also have a key role in the function of nervous, cardiovascular, digestive and other human body systems. Parathyroids are capable of accumulating the isotopes of cesium, strontium and radioactive iodine, which can lead to parathyroid cell damage and emergence of glandular dysfunction. Significant radioactive environmental releases and fallout after the Chernobyl NPP accident in 1...