ea0049ep779 | Endocrine Disruptors | ECE2017
Ajdzanovic Vladimir
, Jaric Ivana
, Zivanovic Jasmina
, Miler Marko
, Ristic Natasa
, Miljic Dragana
, Percinic-Popovska Florina
, Milosevic Verica
Diosgenin, a steroidal sapogenin of natural origin, demonstrated some therapeutic effects when it comes to the treatment of cardiovascular issues, malignancies and the menopausal symptoms. In this study, we have investigated histological changes and corticosterone secretion of the adrenal gland after diosgenin application in a rat model of the menopause. Middle-aged, acyclic female Wistar rats were divided into control (C; n=6) and diosgenin treated (D; n=6) ...