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ea0049gp59 | Cardiovascular & Lipid Endocrinology | ECE2017

Body composition and testosterone determined VO2max in 780 young men – results from the Odense Androgen Study

Christensen Louise Lehmann , Nielsen Torben Leo , Hermann Pernille , Glintborg Dorte , Andersen Marianne

Background: Cardiorespiratory fitness is a measure for physical activity and a prognostic health indicator. However, measurement of maximal oxygen consumption (VO2max) is not possible in clinical practice.Aim: We hypothesized that body composition and testosterone levels could be used as possible determinants of VO2max in young men.Participants and design: The Odense Androgen Study, a population-based, observational study including...

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ea0037gp.13.06 | Diabetes and obesity – Translational cardiovascular and obesity | ECE2015

Effects of testosterone replacement therapy on lean body mass, total fat mass, and insulin sensitivity in aging men with type 2 diabetes - a randomised, double-blinded, placebo-controlled trial

Magnussen Line Velling , Glintborg Dorte , Hermann Pernille , Hougaard David M , Hojlund Kurt , Andersen Marianne S

Lowered testosterone levels may be observed in up to 50% of ageing men with type 2 diabetes (T2D). Testosterone replacement therapy (TRT) increases lean body mass in men with lowered testosterone levels and T2D, but the effect of TRT on glucose metabolism has not been evaluated by euglycemic hyperinsulinemic clamp.We used gold standard methods to evaluate the effect of TRT on body composition, insulin sensitivity, and oxidative metabolism in men with T2D...

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ea0094ec1.3 | Clinical Endocrinology Trust Best Abstract Clinical | SFEBES2023

Biological heterogeneity in skeletal susceptibility to glucocorticoid induced bone loss: Short- and long-term BMD trajectories during unopposed GC treatment in adults

Bakke Hansen Benjamin , Rubin Katrine , Hermann Pernille , Frost Munk Nielsen Morten , Abrahamsen Bo

Objective: Describe short- and long-term changes in BMD in adults exposed to varying intensities of systemic glucocorticoid (GC) treatment.MethodsSetting: Danish Public Health Service Hospital, catchment area 500,000 individuals.Data: BMD data from 2006-2021 and data on filled prescriptions.Analysis: All adult patients with at least two DXA e...

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Endocrine Abstracts

Body composition and testosterone determined VO2max in 780 young men – results from the Odense Androgen Study

Effects of testosterone replacement therapy on lean body mass, total fat mass, and insulin sensitivity in aging men with type 2 diabetes - a randomised, double-blinded, placebo-controlled trial

Biological heterogeneity in skeletal susceptibility to glucocorticoid induced bone loss: Short- and long-term BMD trajectories during unopposed GC treatment in adults

BiosciAbstracts