Searchable abstracts of presentations at key conferences in endocrinology

ea0030p57 | (1) | BSPED2012

Grave problem, unrelated to fracture

Frerichs Carley , Tinklin Tracy

Two weeks after fracturing his humerus a 14-year-old male presented with ongoing epigastric pain and vomiting. He was persistently tachycardic but normotensive. Treatment with intravenous fluids and ranitidine, for a presumed gastritis, was commenced.Initial blood tests revealed a mildly raised urea and creatinine, normal inflammatory markers and full blood count. Further investigation showed a moderate hypercalcaemia with an albumin adjusted calcium of ...

ea0103p20 | Diabetes 1 | BSPED2024

Increasing confidence in managing diabetes in the paediatric emergency department

O'Brien Rachael , Frerichs Carley

Confidence of Emergency Department (ED) Clinicians in the management of Paediatric Type 1 Diabetic (T1DM) Emergencies was investigated at Wythenshawe Hospital to gain an understanding of future training needs. A questionnaire assessing the overall confidence of ED clinicians in the recognition and management of Diabetic Ketoacidosis (DKA), management of children with insulin pump therapy and use of the BSPED sick day rules was circulated. Previous training on this topic in the...

ea0033oc4.3 | Oral Communications 4 | BSPED2013

The incentive trial: do financial rewards improve glycaemic control in teenagers with poorly controlled type 1 diabetes?

Frerichs Carley , Thomas Douglas , Randell Tabitha

Introduction: Adolescence is recognised as a period where compliance to diabetes treatment is challenging and adolescents assume increasing responsibility for their diabetes self-management. In this study we investigated whether giving modest financial rewards motivated teenagers with type 1 diabetes to improve glycaemic control.Methods: Population; young people with type 1 diabetes, age 13–16 years at entry, duration of diabetes of >2 years and...

ea0085p54 | Diabetes 2 | BSPED2022

Technology alone is not the answer for closing the deprivation gap in Type 1 Diabetes Mellitus (T1DM)

Sims Jack , Riddle Miles , Mitchell Thomas , Frerichs Carley

Introduction: Children and young people with T1DM living in the least deprived areas have better diabetes control vs those in most deprived areas with UK NPDA data suggesting that deprivation and ethnicity are associated with less use of technology.1Aims: 1. Review distribution of technology between different socio-economic and ethnic groups 2. To compare mean recent HbA1c results between groups using different combinations of technology<p...

ea0039oc3.1 | Oral Communications 3 | BSPED2015

Long standing autoimmune hypothyroidism with macro-orchidism and pituitary mass: Van Wyk-Grumbach syndrome

Alsaffar Hussain , Phanse Supriya , Frerichs Carley , Didi Mohammed , Senniappan Senthil

Introduction: Van Wyk-Grumbach syndrome was first described in 1960 in patients presenting with long standing juvenile hypothyroidism, delayed bone age and precocious puberty. Literature review indicates only few cases reported in males compared to females. We are reporting this case in a male patient who presented with short stature.Case: A 7.25-year-old boy was referred for endocrine opinion due to short stature. He had not grown over the last 18 month...

ea0033p35 | (1) | BSPED2013

Tired, tachycardic, toxaemic, teenagers: fluids in severe DKA

Frerichs Carley , Davies Patrick , Alurkar Shri , Randell Tabitha , Denvir Louise

DKA guidelines aim to reduce risk of cerebral oedema. We present the outcomes of three young females with severe DKA with reduced conscious level at diagnosis that required deviation from these guidelines.A. 12-year-old, pH 6.88 with DKA and sepsis. Received 20 ml/kg initial fluid bolus. CT head scan was normal. Hypotension required further fluid boluses, inotropes and an increase in fluids to 65% above the rate on DKA protocol. Although slow to wake aft...

ea0039oc2.1 | Oral Communications 2 | BSPED2015

Severe hyponatremia with neurological involvement in a child with adrenal insufficiency

Frerichs Carley , Alsaffar Hussain , Ramakrisnan Renuka , Dharmaraj Poonam , Kumar Ram , Senniappan Senthil , Das Urmi

Case report: A 13-year-old male presented with a 10-day history of vomiting. He was haemodynamically stable. His biochemistry was evaluated revealing a sodium level of 96 mmol/l. He had been seen 2 years previously with short stature. Sodium was normal at this time. He had speech and language delay, learning difficulties and was under investigation for autism. He had reportedly salt craved for years. Potassium, urea, creatinine, and glucose were normal throughout the admission...

ea0036P56 | (1) | BSPED2014

Low birth weight is not a feature of polycystic ovarian syndrome in a British cohort of adolescents, but obesity and metabolic syndrome are common associations

Frerichs Carley , Das Urmi , Dharmaraj Poonam , Didi Mohammed , Hernon Mary , Ramikrishnan Renuka , Blair Jo

Background: Adolescent polycystic ovarian syndrome (PCOS) is being diagnosed more frequently as the prevalence of childhood obesity increases. Adolescent PCOS has been associated with low birth weight (LBW), exaggerated adrenarche (EA) and metabolic syndrome in Mediterranean populations. This study describes the clinical phenotype of a cohort of northern European girls.Methods: A retrospective study of adolescents with PCOS, diagnosed according to the Ro...

ea0103p22 | Diabetes 2 | BSPED2024

HCL use does not cause increased insulin use or change in BMI z-score

O'Brien Rachael , Butterfield Lucy , Turner Louise , Henson Kate , Gray Natasha , Roberts Stephanie , Frerichs Carley , Riddle Miles

56 patients under the care of the paediatric diabetes team at Wythenshawe Hospital were identified as current Omnipod® 5 insulin pump users for Type 1 Diabetes Mellitus management in April 2024. We investigated if use of this HCL caused an increase in daily insulin requirements or an increase in BMI z-score. Time in range (TIR), total daily dose (TDD) of insulin, BMI Z-score along with total daily carbohydrate intake (CHO) and insulin boluses (TDB) during the first six mo...

ea0039ep40 | Diabetes | BSPED2015

Pancreatitis, adrenal insufficiency and autoimmune diabetes mellitus in a girl with probable sarcoidosis

Frerichs Carley , Ramakrishnan Renuka , Alsaffar Hussain , Das Urmi , Dharmaraj Poonam , Baildam Eileen , Cleary Gavin , McCann Liza , Nayak Suneela , Senniappan Senthil

Case report: A 9-year-old girl of mixed ethnic origin presented with symptomatic hypercalcaemia with a 3-month history of weight loss and lethargy. Autoimmune hypothyroidism had been diagnosed 10 months previously. Serum vitamin D concentration (11 nmol/l) was low and cholecalciferol 20 000 units daily for 7 days followed by 800 units daily was commenced. One month later, her symptoms worsened and she had developed anaemia and renal impairment. Hypercalcaemia was noted (Corr C...