Searchable abstracts of presentations at key conferences in endocrinology

ea0099ep262 | Pituitary and Neuroendocrinology | ECE2024

Epidemiology, clinical presentation, treatment and outcome of acromegaly in the island of crete, greece: experience of 3 tertiary centers over a four decade period

Chrysoulaki Maria , Daraki Vasiliki , Sfakiotaki Maria , Tzoutzouraki Paraskevi , Floroskoufi Paraskevi , Betsi Grigoria , Vamvoukaki Rodanthi , Vergou Stavrina , Michailidis Stefanos , Maria Makri Artemis , Mpouhlaki Elpida , Spanoudaki Antonela , Goulielmos Georgios , Lionis Christos , Stamataki Katerina , Xekouki Paraskevi

Acromegaly is a rare and insidious endocrine disease, with increased morbidity and mortality mainly due to delayed diagnosis and inadequate control. There are many population studies assessing the epidemiology of acromegaly in Europe while in Greece, there are no published data except for a few small studies regarding treatment outcome.Aim: To determine the epidemiology, presentation and outcome in patients with acromegaly in Crete, Greece.<p class="...

ea0081ep848 | Pituitary and Neuroendocrinology | ECE2022

Chronic diarrhea: the diagnostic process

Floroskoufi Paraskevi , Vourlioaki Eirini , George Papazoglou , Koukias Stergos , Stamataki Aikaterini

Introduction: Neuroendocrine tumors (NETs) are a heterogeneous group of rare neoplasms that originate from endocrine cells with the ability to secrete amines and hormonal polypeptides. Pancreatic neuroendocrine tumors (PNETs) can be functional or non-functional. Functional PNETs secrete common hormones such as gastrin, insulin and glucagon and much less frequent hormones such as vasoactive intestinal peptide (VIP). Their clinical characteristics depend on the peptide secreted....

ea0081ep1150 | Thyroid | ECE2022

Ectopic cushing’s syndrome : a rare cause

Vourlioaki Eirini , Floroskoufi Paraskevi , Kouloukoura Aspasia , Argyropoulou Eleftheria , Stamataki Aikaterini

Introduction: Medullary thyroid carcinoma (MTC) accounts for 1-5% of all thyroid cancers. It is a neuroendocrine tumor arising from the calcitonin-secreting parafollicular cells of the thyroid. In rare cases, the neoplastic cells additionally secrete other substances, such as histamine, serotonin, ACTH, CRF etc, leading to paraneoplastic syndromes.Case report: An 80 year old male presented to our Department with an already diagnosed metastatic MTC. Three...

ea0041ep331 | Clinical case reports - Thyroid/Others | ECE2016

Overdiagnosis of osteoporosis in a patient with short stature and partial growth hormone insensitivity due to misinterpretation of dual-energy X-ray absorptiometry (DEXA)

Floroskoufi Paraskevi , Daraki Vasiliki , Stratakis John , Kalikakis George , Papavasiliou Stathis

Introduction: Bone densitometry is currently one of the mainstays in the evaluation of systemic bone diseases. The most frequently assessed densitometric parameter is areal bone mineral density (BMD), measured by dual energy X-ray absorptiometry (DEXA) and expressed as g/cm2. However BMD is a bone size-dependent measure and may be found inappropriately low in children and adults with short stature. Osteopenia/osteoporosis have been described in patients with short s...

ea0049gp32 | Adrenal 3 | ECE2017

Multiple pathologic fractures as the presenting manifestation of Cushing’s syndrome in patients with vitamin D receptor FokI gene polymorphism

Daraki Vasiliki , Floroskoufi Paraskevi , Liarigkovinos Theodoros , Chrysoulaki Maria , Tsamadias Vasilios , Economou Emmanuel , Papavasiliou Stathis

Rare cases of Cushing’s syndrome have been diagnosed only based upon bone manifestations. Fracture risk is related to individual susceptibility to glucocorticoids that is genetically determined by several factors, including VDR gene polymorphism.We report three patients with VDR FokI gene polymorphism and multiple non-traumatic pathologic fractures as the presenting manifestation of Cushing’s syndrome.The second case is a...

ea0049ep1418 | Thyroid (non-cancer) | ECE2017

Development of papillary thyroid carcinoma in a patient with multiple solid cell nests of the thyroid

Liarigkovinos Theodoros , Daraki Vasiliki , Floroskoufi Paraskevi , Moustou Helen , Kalikakis George , Papavasiliou Stathis

Introduction: Solid cell nests (SCNs) of the thyroid are considered embryological remnants of the ultimobranchial bodies and the thyroid diverticulum. They are frequently (61–89%) detected in the thyroid gland, but their biological significance remains disputable. According to the fetal cell thyroid carcinogenesis hypothesis SCNs may act as a source for specific thyroid cancer stem cells generating distinct thyroid cancer phenotypes. We report a case of a patient with con...