Endocrine Abstracts

Abstract: There are few studies of the cellular immunity in men with obesity and hypogonadism. The aim was to study the parameters of cellular components of the immune system in patients with obesity and hypogonadism.Materials and methods: The study included 120 men aged 40–65 years with obesity (mean BMI – 35±5.6 kg/m2). Patients were divided into two groups depending on the level of total testosterone (T). The first group incl...

Background: Men with type 2 diabetes mellitus (T2DM) have significantly lower levels of testosterone (T) than nondiabetic controls. But androgen deficit symptoms may be detected in males with normal T levels.Aim: To analyze parameters of lipid, carbohydrate metabolism and endothelial function in diabetic males with low normal and middle-to-high normative T levels.Patients and methods: We examined 86 men with T2DM and serum T levels...

Late identification and inadequate assessment of cardiovascular risk factors are being considered as the main cause of high mortality in men with type 2 diabetes mellitus (T2DM).Aim: To analyze the carbohydrate metabolism, levels of testosterone, proinflammatory cytokines in patients with T2DM and obesity.Methods: We examined 123 men with T2DM and obesity (mean age – 53.8±6.8). Parameters of carbohydrate metabolism, total...

Currently actively studied the role of certain inflammatory and proinflammatory cytokines in the pathogenesis of insulin resistance, type 2 diabetes, obesity, atherosclerosis. However, the influence of testosterone deficiency on the balance of proinflammatory cytokines is unexplored. The aim of the work was to evaluate the influence of testosterone deficiency on metabolic parameters and levels of proinflammatory cytokines in patients with obesity and type 2 diabetes.<p cla...

It is well known that type 2 diabetes causes the endothelial dysfunction. However, insufficient attention is paid to the role of androgen deficiency in the formation of the early signs of endothelial dysfunction. The aim of the work was to evaluate the relationship between testosterone deficiency and markers of endothelial dysfunction in men with type 2 diabetes.Materials and methods: Were examined 88 men aged 40–65 years with type 2 diabetes. All p...