Endocrine Abstracts

Background: Subclinical thyroid hypofunction and elevation of serum lipid concentrations are two factors that may act synergistically in the increase of cardiovascular risk in patients with type 2 diabetes. However, the association between subclinical hypothyroidism and dyslipidemia is a matter of debate.Objective: Our aim has been to assess whether incident hypothyroidism detected in a screening program is accompanied by elevations in the serum concentr...

Aim: Multidisciplinary approach is mandatory in the management of endocrine tumors. Herein, we summarize the healthcare activity performed during the last 6 years at the multidisciplinary committee for endocrine tumors of a tertiary and University Hospital.Methods: A search of clinical-care activity of the endocrine tumors committee of our hospital from 2011 to 2016 was performed. Clinical and demographic data of all patients were recorded. The committee...

Background: The BRAFV600E mutation is the most common mutation in papillary thyroid carcinoma (PTC). Its presence has been associated with extrathyroid invasion, lymph node metastasis, and tumor recurrence. Recently, assessment of the BRAFV600E mutation status in patients with PTC has been used as a method to predict tumor aggressiveness.Objective: Our aim has been to analyze the prevalence of BRAFV60...

Background: Human fibroblast growth factor 21 (FGF21) is a new liver hormone that stimulate adipocyte glucose uptake and is involved in regulation of body fat.Objective: To define the natural history of FGF21 in peritoneal dialysis (PD) patients and analyze its relationship with glucose metabolism, peritoneal function, and residual renal function (RRF).Methods: We studied 48 uremic patients undergoing PD. Patients were evaluated at...

Background: Alterations in thyroid function tests results in patients on peritoneal dialysis (PD) might represent a risk factor for cardiovascular disease (CVD) and mortality.Objective: To investigate the relationship of serum TSH, free thyroxine (FT4), and triiodothyronine (T3) concentrations with incident CVD and mortality in PD patients.Methods: Prospective study including all patients attending our PD unit...