Endocrine Abstracts

Hypocalcemic cardiomyopathy due to hypoparathyroidism is a very rare condition which responds favorably to vitaminocalcic treatment.We report the case of a 50 years old man who presented to our unit for general fatigue, apathy and cough lasting several years with a worsening during the last months, there was biological evidence of hypoparathyroidism with profound hypocalcemia (21 mg/l) hyperphosphoremia (53 mg/l) and undetectable PTH levels the CT scan s...

Galactorrhea (G) is a frequent symptom in endocrinology when breast are systematically examined. In literature there is few works about aetiologies of G. The aim of our work is to evaluate prevalence of G and to study it’s cause in 170 subjects with nipple discharge.Our methodology is based on anamnestic history, clinical exam and a complete hormonal exploration. Women with normal cycle has a temperature curve, endometrial biopsy and progesterone ev...

The main concern of endocrinologist exploring an adrenal incidentaloma (AI) is the identification of malignant and/or secretant AI leading to rapid cure by removal of the tumor. PH remains one of the most difficult lesions to diagnose. In this study we analyze PH clinic, morphologic and secretory profile. Among a series of 91 AI recruited between 1987 and 2007 having benefited from an adrenal exploration, 56 have been removed and 18/56 were diagnosed as tumors of medullar orig...

With the development of medical imaging, many malignant lesions of the adrenal lodge are incidentally discovered. In this prospective monocentric study we are looking for factors of presumption of malignancy in the preoperative stage on a non-oncological series of 91 IS.Monocentric prospective study, AI revealed by TDM±echo supplemented by a clinic/hormonal adrenal exploration ±isotopic. In the absence of against indications, the indication of ...

Studies showed an increase of cardiovascular risk (CVR) and reduction of the life expectancy observed in the anterior pituitary insufficiency (API) subjects. The morbimortality would be related to GH deficiency not substituted.Aim: To seek the frequency of the hypertension and analyse the predictive factors in subjects with API.A retrospective study relating 55 (47 women, eight men) subjects with API: interrupted pituitarystalk n:6...

The GH/IGF axis has been implicated in the pathogenesis of retinopathy in diabetic subjects, the aim of this study is to evaluate the prevalence of diabetic retinopathy in hypersomatotropic patients.Subjects and methods: Twenty four hypersomatotropic patients (12 females, 12 males mean age =49 years, mean hypersomatotropic duration =11 years) have diabetes for 7.25 years in average. To search for diabetic retinopathy a funduscopy was performed in all pat...

Introduction: Glucose metabolism disorder (GMD) is a classic complication of acromegaly, but its frequency varies from study to study.Aim: We aimed to analyze GMD frequency in our population, and predictive factors such as: family history of diabetes mellitus (DM), age, gender, and GH rates.Subjects and methods: It is a prospective study where 75 hypersomatotropic subjects were analyzed. They all had fasting and postprandial blood ...

Although GH has been implicated in the pathogenesis of retinopathy in diabetic subjects, the frequency of retinopathy in diabetic acromegalic subjects is deemed to be rare. The aim of our study is to evaluate the prevalence of retinopathy in hypersomatotropic patients.Subjects and methods: In total, 40 acromegalic diabetic patients (21 M, 19 F, mean age=50 years) underwent funduscopy to search for diabetic retinopathyResults: Among...

IGF1 represent an important key player in several physiologic process, so it can be implicated in different pathologies among delays of growth. A comparative study was realized comparing a group of healthy Algerian children of normal size (n: 266) and a group presenting a GH deficiency (GHD n: 107)to a group of healthy westerners children of normal size(Serie of ROSENFIELD).The results are as follows: Before the age of 04 years, there is a ...

Introduction: Charles Bonnet syndrome is almost unknown by the endocrinologists. It is composed by visual hallucinations that do not react with the patient contrary to psychiatric hallucinations. The abnormal visions (generally hidden by patients) appear in subjects with an impaired vision of one of both eyes as in the following case:Case report: A man aged 27, was referred for acromegaly secondary to a huge invasive somatolactotrope pituitary adenomas d...