ea0049gp18 | Adrenal 2 | ECE2017
Pereira Sofia S
, Costa Madalena M
, Moreira Angela
, Carvalho Liliana
, Monteiro Mariana
, Vinson Gavin
, Pignatelli Duarte
Arterial hypertension usually results from the deregulation and hyperactivity of the renin angiotensin-aldosterone system. One of the available therapeutic approaches for its treatment is the use of mineralocorticoid receptor (MR) antagonists, thus blocking aldosterone action.The aim of this study was to characterize the effects of spironolactone and eplerenone, on the morphology of the adrenal gland of spontaneously hypertensive (SHR) and normotensive (...