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Endocrine Abstracts

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ea0083domno2 | Diabetes, Obesity, Metabolism and Nutrition | EYES2022

Placental signalling contributes to adipokine dysregulation and systemic insulin resistance in gestational diabetes mellitus

C. J. McElwain , A Musumeci , S. Manna , I Sylvester , F. P. McCarthy , C. M. McCarthy

Background: Placental signalling has been postulated to drive inflammation, endothelial dysfunction and insulin resistance in gestational diabetes mellitus (GDM).Objectives: To determine if placental signalling contributes to systemic insulin resistance in GDM.Methods: Adiponectin, leptin, adipsin and resistin in placental and omental explant culture supernatants (n=10 GDM and n=10 control) and maternal plasma (n=20 GDM and n=20 co...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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