ea0049ep883 | Growth hormone IGF axis - basic | ECE2017
Farhat Khalil
, Bodart Gwennaelle
, Renard Chantal
, Desmet Christophe
, Moutschen Michel
, Baron Frederic
, Beguin Yves
, Salvatori Roberto
, Matens Henri
, Geenen Vincent
In the framework of close interactions between the immune and neuroendocrine systems, Growth Hormone (GH) has been proposed to exert significant effects on the immune system, but there is not yet a consensus about GH immunomodulatory properties. These studies investigated the immune and anti-infectious response of dwarf Ghrh−/− mice presenting a severe deficiency of the GHRH/GH/IGF-1 axis. In basal conditions, thymic parameters and T-cell respon...