ea0037ep361 | Diabetes (pathiophysiology & epitemiology) | ECE2015
Bayrakci Nergiz
, Ates Ihsan
, Ozkayar Nihal
, Yilmaz Fatma Meric
, Topcuoglu Canan
, Neselioglu Salim
, Erel Ozcan
, Altay Mustafa
Background: Thiol/disulfide homeostasis plays an important role in antioxidative defense mechanism, detoxification, signal transport, management of enzyme activity and trascription factors, and apoptosis. When thiol/disulphide homeostasis breaks down, these important cellular functions get deranged. Pathologies secondary to oxidative stress are seen in organeles in which this homeostasis is deranged. The aim of the study was to investigate dynamic thiol/disulfide homeostasis i...