Endocrine Abstracts

Objective: Our aim was to present a case of paraneoplastic NMDA-R antibody-mediated limbic encephalitis in a woman with OT thereby providing information facilitating diagnosis of OT in women, who present with symptoms of paraneoplastic limbic encephalitis (LE) for obstetricians and gynaecologists with appropriate.Case: We report the case of a 25-year-old women, who developed NMDA-R-antibody mediated autoimmune encephalitis and who displayed confusion, di...

Introduction: Clinical studies revealed an increased incidence of migraine attacks in conditions with falling levels of plasma oestrogen in the perimenstrual phase of the menstrual cycle and during the hormone-free interval in women taking combined oral contraceptives.Objective: The purpose of the study was to assess the connection between menstrual cycle, bleeding patterns of women with migraine and the clinical characteristics of the migraine attacks.<...

Introduction: Life expectancy is increasing in most developed countries, in part due to improved socio-economic conditions and in part to advances in healthcare. It is widely acknowledged that the promotion of healthy ageing by delaying, minimizing or preventing disabilities or diseases is one of the most important public health objectives in this century.Methods: 243 Women and 181 men aged 40–79 years were recruited in Szeged (Hungary) Subjects wer...

Background: During ageing, total testosterone (TT) declines and SHBG increases, resulting in a greater decline of free testosterone (FT) compared to TT. However, guidelines suggest using TT to diagnose androgen deficiency and to reserve FT only for men with borderline TT. We investigated if isolated low FT or isolated low TT was associated with androgen-related endpoints in healthy men.Methods: 3369 community-dwelling men, aged 40–79, were included....

Introduction: Primary hypogonadism (PHG, testosterone <10.5 nmol/l and LH >9.5 U/l) without a recognisable cause affects ~2% of community-dwelling middle-aged and older men. We sought to identify the clinical significance of, and risk factors for, this apparently age-related hypogonadal state.Methods/design: The European Male Ageing Study (EMAS) is a prospective observational cohort survey of 3.369 community-dwelling men aged 40–79 in eight ...